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Parkinson Disease, Familial, Type 1

MedGen UID:
483744
Concept ID:
C3489791
Disease or Syndrome
Synonyms: Lewy Body Parkinsonism; Parkinson Disease, Autosomal Dominant

Professional guidelines

PubMed

Levin J, Kurz A, Arzberger T, Giese A, Höglinger GU
Dtsch Arztebl Int 2016 Feb 5;113(5):61-9. doi: 10.3238/arztebl.2016.0061. PMID: 26900156Free PMC Article
Hellwig S, Amtage F, Kreft A, Buchert R, Winz OH, Vach W, Spehl TS, Rijntjes M, Hellwig B, Weiller C, Winkler C, Weber WA, Tüscher O, Meyer PT
Neurology 2012 Sep 25;79(13):1314-22. Epub 2012 Aug 22 doi: 10.1212/WNL.0b013e31826c1b0a. PMID: 22914831

Recent clinical studies

Etiology

Búřil J, Búřilová P, Pokorná A, Kováčová I, Baláž M
PLoS One 2021;16(2):e0246342. Epub 2021 Feb 2 doi: 10.1371/journal.pone.0246342. PMID: 33529251Free PMC Article
Voigt DD, Nascimento CM, de Souza RB, Cabello Acero PH, Campos Júnior M, da Silva CP, Pereira JS, Rosso AL, Araujo Leite MA, Vasconcellos LFR, Della Coletta MV, da Silva DJ, Nicaretta DH, Gonçalves AP, Dos Santos JM, Calassara V, Santos-Rebouças CB, Pimentel MMG
Neurobiol Aging 2019 Feb;74:236.e7-236.e8. Epub 2018 Sep 27 doi: 10.1016/j.neurobiolaging.2018.09.026. PMID: 30342766
Fujimoto T, Kuwahara T, Eguchi T, Sakurai M, Komori T, Iwatsubo T
Biochem Biophys Res Commun 2018 Jan 8;495(2):1708-1715. Epub 2017 Dec 6 doi: 10.1016/j.bbrc.2017.12.024. PMID: 29223392
Li NN, Wang L, Tan EK, Cheng L, Sun XY, Lu ZJ, Li JY, Zhang JH, Peng R
Am J Med Genet B Neuropsychiatr Genet 2016 Dec;171(8):1148-1152. Epub 2016 Sep 14 doi: 10.1002/ajmg.b.32498. PMID: 27626775
Badoud S, Van De Ville D, Nicastro N, Garibotto V, Burkhard PR, Haller S
Neuroimage Clin 2016;12:234-40. Epub 2016 Jul 5 doi: 10.1016/j.nicl.2016.07.004. PMID: 27489771Free PMC Article

Diagnosis

Búřil J, Búřilová P, Pokorná A, Kováčová I, Baláž M
PLoS One 2021;16(2):e0246342. Epub 2021 Feb 2 doi: 10.1371/journal.pone.0246342. PMID: 33529251Free PMC Article
Bhatia KP, Stamelou M
Int Rev Neurobiol 2017;134:1285-1301. Epub 2017 Jul 3 doi: 10.1016/bs.irn.2017.06.001. PMID: 28805573
Niccolini F, Politis M
Eur J Nucl Med Mol Imaging 2016 Nov;43(12):2244-2254. Epub 2016 Jul 28 doi: 10.1007/s00259-016-3464-8. PMID: 27470326Free PMC Article
Levin J, Kurz A, Arzberger T, Giese A, Höglinger GU
Dtsch Arztebl Int 2016 Feb 5;113(5):61-9. doi: 10.3238/arztebl.2016.0061. PMID: 26900156Free PMC Article
Eschlböck S, Krismer F, Wenning GK
Parkinsonism Relat Disord 2016 Jan;22 Suppl 1:S82-92. Epub 2015 Sep 25 doi: 10.1016/j.parkreldis.2015.09.038. PMID: 26421389

Therapy

Tolosa E, Vila M, Klein C, Rascol O
Nat Rev Neurol 2020 Feb;16(2):97-107. Epub 2020 Jan 24 doi: 10.1038/s41582-019-0301-2. PMID: 31980808
Eschlböck S, Krismer F, Wenning GK
Parkinsonism Relat Disord 2016 Jan;22 Suppl 1:S82-92. Epub 2015 Sep 25 doi: 10.1016/j.parkreldis.2015.09.038. PMID: 26421389

Prognosis

Southi N, Honan CA, Hodges JR, Piguet O, Kumfor F
Int J Geriatr Psychiatry 2019 Mar;34(3):497-503. Epub 2018 Dec 27 doi: 10.1002/gps.5045. PMID: 30520157
Hall S, Janelidze S, Surova Y, Widner H, Zetterberg H, Hansson O
Sci Rep 2018 Sep 5;8(1):13276. doi: 10.1038/s41598-018-31517-z. PMID: 30185816Free PMC Article
Bhatia KP, Stamelou M
Int Rev Neurobiol 2017;134:1285-1301. Epub 2017 Jul 3 doi: 10.1016/bs.irn.2017.06.001. PMID: 28805573
Niccolini F, Politis M
Eur J Nucl Med Mol Imaging 2016 Nov;43(12):2244-2254. Epub 2016 Jul 28 doi: 10.1007/s00259-016-3464-8. PMID: 27470326Free PMC Article
Hellwig S, Amtage F, Kreft A, Buchert R, Winz OH, Vach W, Spehl TS, Rijntjes M, Hellwig B, Weiller C, Winkler C, Weber WA, Tüscher O, Meyer PT
Neurology 2012 Sep 25;79(13):1314-22. Epub 2012 Aug 22 doi: 10.1212/WNL.0b013e31826c1b0a. PMID: 22914831

Clinical prediction guides

Tolosa E, Vila M, Klein C, Rascol O
Nat Rev Neurol 2020 Feb;16(2):97-107. Epub 2020 Jan 24 doi: 10.1038/s41582-019-0301-2. PMID: 31980808
Yamato Y, Hasegawa T, Togawa D, Yoshida G, Yasuda T, Banno T, Oe S, Arima H, Mihara Y, Ushirozako H, Kobayashi S, Matsuyama Y
Spine (Phila Pa 1976) 2020 Feb 15;45(4):E217-E226. doi: 10.1097/BRS.0000000000003246. PMID: 31513098
Lorenzo-Betancor O, Ogaki K, Soto-Ortolaza AI, Labbe C, Walton RL, Strongosky AJ, van Gerpen JA, Uitti RJ, McLean PJ, Springer W, Siuda J, Opala G, Krygowska-Wajs A, Barcikowska M, Czyzewski K, McCarthy A, Lynch T, Puschmann A, Rektorova I, Sanotsky Y, Vilariño-Güell C, Farrer MJ, Ferman TJ, Boeve BF, Petersen RC, Parisi JE, Graff-Radford NR, Dickson DW, Wszolek ZK, Ross OA
Eur J Neurol 2015 Sep;22(9):1323-5. doi: 10.1111/ene.12770. PMID: 26278106Free PMC Article
Bhidayasiri R, Jitkritsadakul O, Petchrutchatachart S, Kaewwilai L, Panyakaew P, Boonrod N, Colosimo C
J Neural Transm (Vienna) 2014 Aug;121 Suppl 1:S69-77. Epub 2014 Mar 26 doi: 10.1007/s00702-014-1198-y. PMID: 24668247
Lee CN, Kim M, Lee HM, Jang JW, Lee SM, Kwon DY, Park KW, Koh SB
J Neurol Sci 2013 Apr 15;327(1-2):15-21. Epub 2013 Feb 18 doi: 10.1016/j.jns.2013.01.034. PMID: 23428208

Recent systematic reviews

Rana AQ, Qureshi AR, Siddiqui O, Sarfraz Z, Rana R, Shtilbans A
J Neurol 2019 Sep;266(9):2093-2102. Epub 2018 Sep 20 doi: 10.1007/s00415-018-9049-7. PMID: 30238268
Niccolini F, Politis M
Eur J Nucl Med Mol Imaging 2016 Nov;43(12):2244-2254. Epub 2016 Jul 28 doi: 10.1007/s00259-016-3464-8. PMID: 27470326Free PMC Article

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